Trazodone helps with sleep by calming brain activity and supporting the body’s natural sleep process. At low doses, it works by increasing serotonin activity, a neurotransmitter involved in regulating mood and sleep, while also blocking certain receptors linked to wakefulness, including histamine and alpha-1 adrenergic receptors. This combination reduces nighttime alertness and mental arousal, making it easier to fall asleep and stay asleep. Rather than acting as a traditional sleeping pill, trazodone helps the brain shift into sleep more naturally, which is why it is commonly used as a non-habit-forming option for sleep support under medical supervision.
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